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1

Protein content and amino acid composition of commercially available plant-based protein isolates

Gorissen, Stefan H. M., Crombag, Julie J. R., Senden, Joan M. G., Waterval, W. A. Huub, Bierau, Jörgen, Verdijk, Lex B., van Loon, Luc J. C.

Journal:

Year:

2018

Language:

english

File:

PDF, 820 KB

english, 2018

2

Degradation of an Fc-fusion recombinant protein by host cell proteases: Identification of a CHO cathepsin D protease

Flavie Robert, Horst Bierau, Mara Rossi, David Agugiaro, Thomas Soranzo, Hervé Broly, Christine Mitchell-Logean

Journal:

Biotechnology and Bioengineering

Year:

2009

Language:

english

File:

PDF, 595 KB

english, 2009

3

The unfolding clinical spectrum of POLG mutations

Blok, M J, van den Bosch, B J, Jongen, E, Hendrickx, A, de Die-Smulders, C E, Hoogendijk, J E, Brusse, E, de Visser, M, Poll-The, B T, Bierau, J, de Coo, I F, Smeets, H J

Journal:

Journal of Medical Genetics

Year:

2009

Language:

english

File:

PDF, 300 KB

english, 2009

4

Extended diagnosis of purine and pyrimidine disorders from urine: LC MS/MS assay development and clinical validation

Monostori, Péter, Klinke, Glynis, Hauke, Jana, Richter, Sylvia, Bierau, Jörgen, Garbade, Sven F., Hoffmann, Georg F., Langhans, Claus-Dieter, Haas, Dorothea, Okun, Jürgen G., Dzeja, Petras

Journal:

Year:

2019

Language:

english

File:

PDF, 1.43 MB

english, 2019

5

Glycoengineered Antibodies: Towards the Next-Generation of Immunotherapeutics

Mastrangeli, Renato, Palinsky, Wolf, Bierau, Horst

Journal:

Year:

2018

Language:

english

File:

PDF, 3.04 MB

english, 2018

6

The Formidable Challenge of Controlling High Mannose-Type N-Glycans in Therapeutic mAbs

Mastrangeli, Renato, Audino, Maria Concetta, Palinsky, Wolf, Broly, HervÃ©, Bierau, Horst

Journal:

Trends in Biotechnology

Year:

2020

File:

PDF, 1.09 MB

2020

7

Direct process integration of cell disruption and fluidised bed adsorption for the recovery of intracellular proteins

Horst Bierau, Zhanren Zhang, Andrew Lyddiatt

Journal:

Journal of Chemical Technology & Biotechnology

Year:

1999

Language:

english

File:

PDF, 138 KB

english, 1999

8

Characterisation of a Novel Growth Hormone Variant Comprising a Thioether Link between Cys182 and Cys189

Antonio Datola, Sophie Richert, Horst Bierau, David Agugiaro, Anna Izzo, Mara Rossi, David Cregut, Hélène Diemer, Christine Schaeffer, Alain Van Dorsselaer, Carlo Emanuele Giartosio, Carl Jone

Journal:

Year:

2007

Language:

english

File:

PDF, 787 KB

english, 2007

9

Cyclopentenyl cytosine primes SK-N-BE(2)c neuroblastoma cells for cytarabine toxicity

Jörgen Bierau, Albert H. van Gennip, René Leen, Jozien Helleman, Huib N. Caron, André B.P. van Kuilenburg

Journal:

International Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 136 KB

english, 2003

10

Heterogeneity of commercial recombinant human growth hormone (r-hGH) preparations containing a thioether variant

Monica Lispi, Antonio Datola, Horst Bierau, Domenico Ceccarelli, Carmelina Crisci, Katia Minari, Daniele Mendola, Aniello Regine, Cinzia Ciampolillo, Mara Rossi, Carlo Emanuele Giartosio, Anna Rita Pe

Journal:

Journal of Pharmaceutical Sciences

Year:

2009

Language:

english

File:

PDF, 253 KB

english, 2009

11

Determination of the deoxycytidine kinase activity in cell homogenates with a non-radiochemical assay using reversed-phase high performance liquid chromatography: Identification of a novel metabolite of 2-chlorodeoxyadenosine

Jörgen Bierau, René Leen, Albert H.van Gennip, Huib N. Caron, André B.P.van Kuilenburg

Journal:

Journal of Chromatography B

Year:

2004

Language:

english

File:

PDF, 127 KB

english, 2004

12

Niobium-doped TiO2 films as window layer for chalcopyrite solar cells

Bernhard Neumann, Frauke Bierau, Benjamin Johnson, Christian Alexander Kaufmann, Klaus Ellmer, Helmut Tributsch

Journal:

physica status solidi (b)

Year:

2008

Language:

english

File:

PDF, 603 KB

english, 2008

13

Cyclopentenyl cytosine-induced activation of deoxycytidine kinase increases gemcitabine anabolism and cytotoxicity in neuroblastoma

Jörgen Bierau, Albert H. van Gennip, René Leen, Rutger Meinsma, Huib N. Caron, André B. P. van Kuilenburg

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2006

Language:

english

File:

PDF, 286 KB

english, 2006

14

Analysis of severely affected patients with dihydropyrimidine dehydrogenase deficiency reveals large intragenic rearrangements ofDPYDand a de novo interstitial deletion del(1)(p13.3p21.3)

André B. P. van Kuilenburg, Judith Meijer, Adri N. P. M. Mul, Raoul C. M. Hennekam, Jan M. N. Hoovers, Christine E. M. de Die-Smulders, Peter Weber, Andrea Capone Mori, Jörgen Bierau, Brian Fowler, Kl

Journal:

Year:

2009

Language:

english

File:

PDF, 537 KB

english, 2009

15

Gas-phase IR spectra of intact α-helical coiled coil protein complexes

Kevin Pagel, Peter Kupser, Frauke Bierau, Nicolas C. Polfer, Jeffrey D. Steill, Jos Oomens, Gerard Meijer, Beate Koksch, Gert von Helden

Journal:

International Journal of Mass Spectrometry

Year:

2009

Language:

english

File:

PDF, 751 KB

english, 2009

16

The pharmacokinetic effect of discontinuation of mesalazine on mercaptopurine metabolite levels in inflammatory bowel disease patients

L. P. L. GILISSEN, J. BIERAU, L. J. J. DERIJKS, L. P. BOS, P. M. HOOYMANS, A. VAN GENNIP, R. W. STOCKBRÜGGER, L. G. J. B. ENGELS

Journal:

Alimentary Pharmacology & Therapeutics

Year:

2005

Language:

english

File:

PDF, 118 KB

english, 2005

17

Direct process integration of cell disruption and fluidised bed adsorption in the recovery of labile microbial enzymes

Horst Bierau, Roger J. Hinton, Andrew Lyddiatt

Journal:

Year:

2001

Language:

english

File:

PDF, 1.38 MB

english, 2001

18

A novel multiparameter flow cytometric assay for inosine triphosphatase expression analysis in leukocytes

Wim H. M. Vroemen, Imke C. A. Munnix, Jaap A. Bakker, Jörgen Bierau, Mark Huts, Mathie P. G. Leers

Journal:

Cytometry Part A

Year:

2012

Language:

english

File:

PDF, 2.32 MB

english, 2012

19

The cytostatic- and differentiation-inducing effects of cyclopentenyl cytosine on neuroblastoma cell lines

Jörgen Bierau, Albert H. van Gennip, Jozien Helleman, André B.P. van Kuilenburg

Journal:

Biochemical Pharmacology

Year:

2001

Language:

english

File:

PDF, 144 KB

english, 2001

20

A comparative study of inosine triphosphatase activity in fresh erythrocytes and dried blood spots

Jaap A. Bakker, Martijn Lindhout, Lambertus Dorland, Jörgen Bierau

Journal:

Clinica Chimica Acta

Year:

2009

Language:

english

File:

PDF, 107 KB

english, 2009

21

Quantitative UPLC-MS/MS analysis of underivatised amino acids in body fluids is a reliable tool for the diagnosis and follow-up of patients with inborn errors of metabolism

W.A. Huub Waterval, Jean L.J.M. Scheijen, Marjon M.J.C. Ortmans-Ploemen, Catharina D. Habets-van der Poel, Jörgen Bierau

Journal:

Clinica Chimica Acta

Year:

2009

Language:

english

File:

PDF, 180 KB

english, 2009

22

Direct non-radioactive assay of galactose-1-phosphate:uridyltransferase activity using high performance liquid chromatography

Martijn Lindhout, M. Estela Rubio-Gozalbo, Jaap A. Bakker, Jörgen Bierau

Journal:

Clinica Chimica Acta

Year:

2010

Language:

english

File:

PDF, 296 KB

english, 2010

23

MGMT promoter hypermethylation correlates with a survival benefit from temozolomide in patients with recurrent anaplastic astrocytoma but not glioblastoma

J. Sadones, A. Michotte, P. Veld, C. Chaskis, R. Sciot, J. Menten, E.J.R. Joossens, T. Strauven, L.A. D’Hondt, D. Sartenaer, S.F.E.H. Califice, K. Bierau, C. Svensson, J. De Grève, B. Neyns

Journal:

European Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 153 KB

english, 2009

24

Structural characterisation of the hepatitis C envelope glycoprotein E1 ectodomain derived from a mammalian and a yeast expression system

Eric Lorent, Horst Bierau, Yves Engelborghs, Gert Verheyden, Fons Bosman

Journal:

Year:

2008

Language:

english

File:

PDF, 444 KB

english, 2008

25

Decreased oxidative phosphorylation and PGAM deficiency in horses suffering from atypical myopathy associated with acquired MADD

C.M. Westermann, L. Dorland, O.P. van Diggelen, K. Schoonderwoerd, J. Bierau, H.R. Waterham, J.H. van der Kolk

Journal:

Molecular Genetics and Metabolism

Year:

2011

Language:

english

File:

PDF, 176 KB

english, 2011

26

Retinoic acid reduces the cytotoxicity of cyclopentenyl cytosine in neuroblastoma cells

Jörgen Bierau, Albert H van Gennip, René Leen, Huib N Caron, André B.P van Kuilenburg

Journal:

Year:

2002

Language:

english

File:

PDF, 120 KB

english, 2002

27

Primary ovarian insufficiency in classic galactosemia: role of FSH dysfunction and timing of the lesion

Gubbels, Cynthia S., Land, Jolande A., Evers, Johannes L. H., Bierau, Jörgen, Menheere, Paul P. C. A., Robben, Simon G. F., Rubio-Gozalbo, M. Estela

Journal:

Journal of Inherited Metabolic Disease

Year:

2013

Language:

english

File:

PDF, 132 KB

english, 2013

28

Therapeutic drug monitoring of thiopurine metabolites in adult thiopurine tolerant IBD patients on maintenance therapy

Lennard P.L. Gilissen, Dennis R. Wong, Leopold G.J.B. Engels, Jörgen Bierau, Jaap A. Bakker, Aimée D.C. Paulussen, Mariëlle J. Romberg-Camps, Arnold Stronkhorst, Paul Bus, Laurens P. Bos, Piet M. Hooy

Journal:

Journal of Crohn's and Colitis

Year:

2012

Language:

english

File:

PDF, 546 KB

english, 2012

29

Pancytopenia due to high 6-methylmercaptopurine levels in a 6-mercaptopurine treated patient with Crohn's disease

L.P.L. Gilissen, L.J.J. Derijks, H.M.J.H. Verhoeven, J. Bierau, P.M. Hooymans, D.W. Hommes, L.G.J.B. Engels

Journal:

Digestive and Liver Disease

Year:

2007

Language:

english

File:

PDF, 326 KB

english, 2007

30

A comparison of intensive cell culture bioreactors operating with Hybridomas modified for inhibited apoptotic response.

H Bierau, A Perani, M Al-Rubeai, A.N Emery

Journal:

Journal of Biotechnology

Year:

1998

Language:

english

File:

PDF, 698 KB

english, 1998

31

12LBA A Plasma-based colorectal cancer (CRC) screening assay using DNA methylation markers - first results of multicenter studies

J. Louwagie, W. Pommerien, G. Brichard, G. Otto, W. Van Criekinge, S.B. Baylin, N. Ahuja, H.P. Adams, D. Nürnberg, K. Bierau

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

PDF, 44 KB

english, 2009

32

PP129 Molecular biomarker analysis of clinical prostate biopsy specimens: Tissue print techniques simplify development of DNA methylation marker tests while preserving the FFPE specimen for histology

S. Gaston, A. Guerra, J. Meadows, J. Bigley, I. Renard, J. Louwagie, K. Bierau

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

PDF, 62 KB

english, 2009

33

Pharmacogenetic significance of inosine triphosphatase

Bierau, Jörgen, Lindhout, Martijn, Bakker, Jaap A

Journal:

Pharmacogenomics

Year:

2007

Language:

english

File:

PDF, 258 KB

english, 2007

34

Biochemical abnormalities in a patient with thymidine phosphorylase deficiency with fatal outcome

Bakker, Jaap A., Schlesser, Patrick, Smeets, Hubert J. M., Francois, Baudouin, Bierau, Jörgen

Journal:

Journal of Inherited Metabolic Disease

Year:

2010

Language:

english

File:

PDF, 131 KB

english, 2010

35

Erratum zu: Hygienemaßnahmen bei Infektionen oder Besiedlung mit multiresistenten gramnegativen Stäbchen. Empfehlung der Kommission für Krankenhaushygiene und Infektionsprävention (KRINKO) beim Robert Koch-Institut (RKI)

Bakker, Jaap A., Schlesser, Patrick, Smeets, Hubert J. M., Francois, Baudouin, Bierau, Jörgen

Journal:

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

Year:

2013

Language:

german

File:

PDF, 131 KB

german, 2013

36

W1874 Promoter Hypermethylation of PHACTR3, a Potential New Biomarker for Colorectal Cancer Detection

Bosch, Linda J., Neerincx, Maarten, Oort, Frank A., Mongera, Sandra, Masclee, Ad, Jonkers, Daisy, Khalid-de Bakker, Carolina, Bierau, Katja, Louwagie, Joost, van Criekinge, Wim, de Bruine, Adriaan P.,

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 111 KB

english, 2009

37

In vitro biological characterization of IFN- -1a major glycoforms

Mastrangeli, R., Rossi, M., Mascia, M., Palinsky, W., Datola, A., Terlizzese, M., Bierau, H.

Journal:

Year:

2015

Language:

english

File:

PDF, 963 KB

english, 2015

38

Secondary Structure of Ac-Ala n -LysH + Polyalanine Peptides ( n = 5,10,15) in Vacuo: Helical or Not?

Rossi, Mariana, Blum, Volker, Kupser, Peter, von Helden, Gert, Bierau, Frauke, Pagel, Kevin, Meijer, Gerard, Scheffler, Matthias

Journal:

The Journal of Physical Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 2.67 MB

english, 2010

39

Catching Proteins in Liquid Helium Droplets

Bierau, Frauke, Kupser, Peter, Meijer, Gerard, von Helden, Gert

Journal:

Physical Review Letters

Year:

2010

Language:

english

File:

PDF, 393 KB

english, 2010

40

Determination of ITPase Activity in Erythrocyte Lysates Obtained for Determination of Tpmt Activity

Bierau, J., Bakker, J. A., Lindhout, M., van Gennip, A. H.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2006

Language:

english

File:

PDF, 77 KB

english, 2006

41

An HPLC-Based Assay of Adenylosuccinate Lyase in Erythrocytes

Bierau, Jörgen, Pooters, Ivo N. A., Visser, Dennis, Bakker, Jaap A.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2011

Language:

english

File:

PDF, 269 KB

english, 2011

42

The Effect of ITPA Polymorphisms on the Enzyme Kinetic Properties of Human Erythrocyte Inosine Triphosphatase Toward its Substrates ITP and 6-Thio-ITP

Bakker, Jaap A., Lindhout, Martijn, Habets, Daphna D.J., van den Wijngaard, Arthur, Paulussen, Aimee D.C., Bierau, Jörgen

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2011

Language:

english

File:

PDF, 233 KB

english, 2011

43

Near Infrared Fluorescence Imaging for early detection, monitoring and improved intervention of diseases involving the joint

Slooter, M. D., Bierau, K., Chan, A. B., Löwik, C. W. G. M.

Journal:

Connective Tissue Research

Year:

2015

Language:

english

File:

PDF, 389 KB

english, 2015

44

Prostate Cancer Detected by Methylated Gene Markers in Histopathologically Cancer-Negative Tissues from Men with Subsequent Positive Biopsies

Troyer, D. A., Lucia, M. S., de Bruine, A. P., Mendez-Meza, R., Baldewijns, M. M., Dunscomb, N., Van Engeland, M., McAskill, T., Bierau, K., Louwagie, J., Bigley, J. W.

Journal:

Cancer Epidemiology Biomarkers & Prevention

Year:

2009

Language:

english

File:

PDF, 500 KB

english, 2009

45

Therapeutic regimens in interstitial lung disease guided by genetic screening: fact or fiction?

Bakker, J. A., Bierau, J., Drent, M.

Journal:

European Respiratory Journal

Year:

2007

Language:

english

File:

PDF, 108 KB

english, 2007

46

Properties of Anodically Oxidized Polycrystalline Silicon Layers

Wagner, Sigurd, Otto, T., Bierau, F.

Journal:

Solid State Phenomena

Year:

1994

File:

PDF, 223 KB

1994

47

A role for ITPA variants in the clinical course of pulmonary Langerhans' cell histiocytosis?

Bakker, J. A., Bierau, J., Drent, M.

Journal:

European Respiratory Journal

Year:

2010

Language:

english

File:

PDF, 188 KB

english, 2010

48

Digital Droplet PCR for Rapid Quantification of Donor DNA in the Circulation of Transplant Recipients as a Potential Universal Biomarker of Graft Injury

Beck, J., Bierau, S., Balzer, S., Andag, R., Kanzow, P., Schmitz, J., Gaedcke, J., Moerer, O., Slotta, J. E., Walson, P., Kollmar, O., Oellerich, M., Schutz, E.

Journal:

Clinical Chemistry

Year:

2013

Language:

english

File:

PDF, 3.23 MB

english, 2013

49

Quantitative analysis of O6-alkylguanine-DNA alkyltransferase in malignant glioma

Maxwell, J. A., Johnson, S. P., Quinn, J. A., McLendon, R. E., Ali-Osman, F., Friedman, A. H., Herndon, J. E., Bierau, K., Bigley, J., Bigner, D. D., Friedman, H. S.

Journal:

Molecular Cancer Therapeutics

Year:

2006

Language:

english

File:

PDF, 190 KB

english, 2006

50

Metabolic inactivation of five glycidyl ethers in lung and liver of humans, rats and mice in vitro

Boogaard, P. J., De Kloe, K. P., Bierau, J., Kuiken, G., Borkulo, P. E. D., Van Sittert, N. J.

Journal:

Year:

2000

Language:

english

File:

PDF, 296 KB

english, 2000

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